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3 There is no evidence of functional differences between GSTM1a and GSTM1b , which differ by a substitution in one base pair

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Diabetics and others with impaired glucose tolerance are highly susceptible to the tissue-damaging effects of advanced protein glycation, a process that occurs when blood sugar reacts with body proteins resulting in various accumulated destructive effects on blood vessels, nerves, and the lens of the eye

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) have already made it into practice due to favorable risk-benefit profiles